Source Naturals HydroxoCobalamin, Vitamin B-12, 1 mg - 120 Cherry Flavored Lozenges

easy to take, taste ok, seem to do the job. thanks

If you've used 23andme, you won't find direct discussion of the MTHFR gene defect. You'd need to run your data through Genetic Genie. The MTHFR defect is not uncommon, and it's not a strict binary "good/horrible" sort of thing - depends on many variables. But the core issue is impairments to Methylation, which is involved in many core biological functions.In my case, it seems to be an impairment in the sense that methyl-based supplements cause 'depressive' mood changes rather than 'brightening' my mood (all pretty minimal, but noticeable).What does all this gobbledygook mean? If I take MethylCobalamin, it doesn't bring my mood up, it takes it down (again, not dramatically). However, HydroxoCobalamin doesn't have this effect. It works just fine, except for the tendency of all B12's to cause some acne in the days after using it.Other than that, it works great. Highly recommended!

Some recent genetic testing results revealed that I am sensitive to the form of B12 I’ve been taking for years and this form was recommended. I was so happy to find it on Amazon and to know I’m finally getting what my body needs. The lozenges are pleasant tasting and dissolve pretty quickly. I recently also learned that taking B12 with vitamin C can reduce the amount of B12 available in your body, so it was recommended to take this two hours apart from Vitamin C supplements. I’ve been taking it after lunch and that has worked well. I would also recommend not taking this too late in the day. The one time I did, I had unusual (for me) insomnia and that’s the only thing I could connect it to. Overall, I’m very happy with this product and am grateful to be able to get it on Amazon.

But now that I found out that this type of B12 is actually a detoxing B12 having an MTHFR issue I’m gonna alternate the Two this one in the morning and the methyl at night

Flavor is bad but, I like this form of vitamin b12. It completely dissolves which is nice, no grittiness.

In the 21st Century, we're learning about genetics and DNA methylation more than ever before. Many people have genetic mutations which cause us to react badly to other forms of Vitamin B12. For me, I get rashes and unpleasant mood changes from cyanocobalamin and methylcobalamin. Hydroxocobalamin works for the super-sensitive, genetically different (gifted) people who react to the others.If you have a similar experience and wonder why vitamin b12 tends to give you rashes, make you flushed, or makes you wig out, this might be a better option to try. You also might do a DNA self-analysis by using one of the most common services to take a saliva test; then, input the results into a third-party service that helps you better understand your unique DNA methylation patterns.The cherry flavor is a nice bonus.

My new bl00d results are in and I've dramatically improved from these!!No side effectsEasy on the gut

Tried this on 5 different occasions, and every time it made my stomach feel really bad. I blame the sugar alcohols in the ingredients. oh well.