Life Extension Same 400mg (S-Adenosyl-Methionine) - Supplement for Joint & Liver Support - Non-GMO, Gluten-Free, Tablet, 60 Count

Good product worked really well

I have been taking Sam-E for years for my joints. I recently switched to this brand from another popular name brand and have not noticed any degradation in how it works and my pocketbook is happier! These are sealed in foil, which is how they should be packaged. No complaints, these are working as expected. They also seem to give an uplift in my mood as well (or is that the lower cost?).EDIT: I am still using this product months later and it is still working as expected.

Highly recommend Sam-e to those with seasonal depression.Been taking this supplant for many years; growing up in AK with the long dark season I never had to take antidepressants. Amazing product.

Great option

I bought this for the past year and it's amazing. My mood, joint issues, and bruxism drastically improved immediately. Sadly, the price just shot up 25% since January from $39 to $49. You all know there are other brands, right? As long as the price is so high I will be purchasing from another manufacturer.

This stuff is night and day for me at least. Helps balance mood, anxiety and overall feeling of down and out. Recently went through a bit of trauma. Without this, would have been much more challenging. I recommend this product.

I've heard folks say amazon life extensions are fake. This is real, hands down.

Never without SAMe. Not only is it good for your mood but it's also good for your joints. I take it at the same time every night. Keep the box right by my bedside.