---
product_id: 430327437
title: "Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules)"
brand: "designs for health"
price: "₪521"
currency: ILS
in_stock: false
reviews_count: 5
category: "Designs For Health"
url: https://www.desertcart.co.il/products/430327437-designs-for-health-same-capsules-with-b6-b12-5-mthf
store_origin: IL
region: Israel
---

# 200mg stabilized SAMe per capsule 5-MTHF folate + B12 cofactors for methylation Patented tech protects SAMe from stomach acid Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules)

**Brand:** designs for health
**Price:** ₪521
**Availability:** ❌ Out of Stock

## Summary

> 💥 Elevate your mental edge & immune resilience with every capsule!

## Quick Answers

- **What is this?** Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) by designs for health
- **How much does it cost?** ₪521 with free shipping
- **Is it available?** Currently out of stock
- **Where can I buy it?** [www.desertcart.co.il](https://www.desertcart.co.il/products/430327437-designs-for-health-same-capsules-with-b6-b12-5-mthf)

## Best For

- designs for health enthusiasts

## Why This Product

- Trusted designs for health brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Clean & Conscious Formula:** Non-GMO, gluten-free, vegetarian-friendly — wellness without compromise.
- • **Trusted by 50,000+ Doctors:** Backed by science and professional-grade quality since 1989.
- • **Cutting-Edge Stability Tech:** Patented powder shields SAMe from degradation, ensuring maximum absorption.
- • **Clinically Potent 200mg SAMe:** Power your mood & cellular health with a precise, stabilized dose.
- • **Synergistic B-Vitamin Complex:** B6, B12 & 5-MTHF optimize natural methylation pathways for peak performance.

## Overview

Designs for Health SAMe Capsules deliver a potent 200mg dose of stabilized S-Adenosylmethionine combined with essential cofactors B6, B12, and 5-MTHF folate. Utilizing patented technology, these capsules protect SAMe from stomach acid, ensuring superior absorption in the small intestine. This non-GMO, gluten-free, and vegetarian-friendly formula supports neurotransmitter synthesis, immune function, and cellular methylation, making it a top choice among health professionals since 1989.

## Description

SAMe is a naturally occurring metabolite found in the human body as well as in plant and animal foods. It is the most active of all methyl donors and has been compared to ATP in its importance for the body. SAMe is naturally synthesized in humans from the amino acid methionine in the presence of the cofactors B12 and folate. SAMe is involved in the synthesis of neurotransmitters, the hormone melatonin, phospholipids, and polyamines, which control cellular growth. It is also the source of methyl groups inside the nucleus for DNA methylation, which controls gene expression and masking of genetic damage. These capsules provide 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF in order to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine. Made with non-GMO ingredients.

Review: We did a lot of research - actually a ridiculous amount - to identify the safest, purest, and least likely to cause unwanted side effects. We also asked several doctors about various brands. Designs for Health was consistently mentioned as being the most effective with extremely high quality control. This is particularly important for SAMe because the compounds apparently breakdown quite easily if not manufactured or packaged properly. Our son has been on this for almost 2yrs and it has worked very well.
Review: This supplement has been awesome for my son who has depression/anxiety. It has taken alot of the symptoms away and has also given him energy!!! He also eats healthy and exercises daily so make sure you do this as well because it is very important.

## Features

- Immune And Hormone Support - S-Adenosylmethionine or SAMe is a naturally occurring compound found in the human body as well as in plant and animal foods. It is involved in many processes throughout the body. SAMe plays a role in supporting the immune system and maintaining cell membranes, the protective barrier that surrounds all cells. It also helps to produce neurotransmitters like melatonin- that helps with your body's rest cycle, and serotonin, the "feel good" hormone. *
- Includes Necessary Cofactors - Each capsule provides 200 mg of SAMe along with vitamins B6, B12, and folate as 5-MTHF to provide cofactors for the natural conversions of SAMe to L-homocysteine and then safely to L-cysteine. *
- Special Technology - Our SAMe capsules are made using special technology with a patented stabilized powder which protects the SAMe from being destroyed by air and moisture. This cutting-edge technology prevents its breakdown by stomach acidity and allows the capsule to be absorbed intact in the small intestine. *
- Always Pure & Effective Products - This product is Vegetarian-Friendly, Non-GMO, and contains No Gluten, Dairy, or Soy.*
- Over 50,000 Doctors Agree - Designs for Health is the physician's choice for top quality professional strength supplements since 1989. Our "Science First" philosophy ensures our products are based on the most recent research and use the highest quality raw ingredients.

## Technical Specifications

| Specification | Value |
|---------------|-------|
| ASIN | B00B9EF6KA |
| ASIN  | B00B9EF6KA |
| Additives | Gluten Free |
| Age Range Description | Adult |
| Best Sellers Rank | #160,809 in Health ( See Top 100 in Health ) #1,336 in Vitamin B Supplements |
| Brand | designs for health |
| Customer Reviews | 4.6 4.6 out of 5 stars (98) |
| Customer reviews | 4.6 4.6 out of 5 stars (98) |
| Date First Available | 27 May 2013 |
| Format | Capsule |
| Is Discontinued By Manufacturer  | No |
| Item model number  | SAM030 |
| Manufacturer  | Designs for Health |
| Product Dimensions  | 5.72 x 7.62 x 10.16 cm; 118 g |
| Serving Recommendation | One Capsule |
| Units | 30 Count |
| Weight | 0.3 Kilograms |

## Product Details

- **Age range (description):** Adult
- **Brand:** designs for health
- **Diet type:** Gluten Free, Vegetarian
- **Flavour:** Unflavored
- **Item dimensions L x W x H:** 5.7 x 7.6 x 10.2 centimeters
- **Item form:** Capsule
- **Primary supplement type:** Vitamin-b
- **Product benefits:** Brain Health Support
- **Special ingredients:** Gluten Free
- **Unit count:** 30 Count

## Images

![Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) - Image 1](https://m.media-amazon.com/images/I/713Oxu2d5mL.jpg)
![Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) - Image 2](https://m.media-amazon.com/images/I/713g3FusP-L.jpg)
![Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) - Image 3](https://m.media-amazon.com/images/I/71bEZyN-CgL.jpg)
![Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) - Image 4](https://m.media-amazon.com/images/I/71obsWgSkUL.jpg)
![Designs for Health SAMe Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules) - Image 5](https://m.media-amazon.com/images/I/71qcAXwVe5L.jpg)

## Customer Reviews

### ⭐⭐⭐⭐⭐ Review
*by J***. on 14 June 2022*

We did a lot of research - actually a ridiculous amount - to identify the safest, purest, and least likely to cause unwanted side effects. We also asked several doctors about various brands. Designs for Health was consistently mentioned as being the most effective with extremely high quality control. This is particularly important for SAMe because the compounds apparently breakdown quite easily if not manufactured or packaged properly. Our son has been on this for almost 2yrs and it has worked very well.

### ⭐⭐⭐⭐⭐ Review
*by C***R on 28 January 2020*

This supplement has been awesome for my son who has depression/anxiety. It has taken alot of the symptoms away and has also given him energy!!! He also eats healthy and exercises daily so make sure you do this as well because it is very important.

### ⭐⭐⭐⭐⭐ Review
*by S***N on 16 September 2018*

I love this Brand. Their products are exactly as described. This product is Non-GMO, Gluten-Free, and Vegetarian-friendly. Their products do exactly what they are suppose to do. The only thing I don't like about them is they are so expensive. I tried another brand (NOW) but it was not as good at all. It was so bad that I re-ordered this one even though it is expensive. This one really works!

## Frequently Bought Together

- Designs for Health Same Capsules with B6, B12 + 5-MTHF - 200mg S-Adenosylmethionine Supplement with 5-MTHF (Folate) + Vitamin B12 - Non-GMO + Gluten-Free (30 Capsules)
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*Product available on Desertcart Israel*
*Store origin: IL*
*Last updated: 2026-01-28*