---
product_id: 254553883
title: "Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs Over 55 lb 710546040004"
brand: "k9 advantix"
price: "₪457"
currency: ILS
in_stock: true
url: https://www.desertcart.co.il/products/254553883-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-x
store_origin: IL
region: Israel
---

# Waterproof formula Starts working in 12h 5-way repel & kill Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs Over 55 lb 710546040004

**Brand:** k9 advantix
**Price:** ₪457
**Availability:** ✅ In Stock

## Summary

> 🐾 Keep your big buddy pest-free and unstoppable!

## Quick Answers

- **What is this?** Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs Over 55 lb 710546040004 by k9 advantix
- **How much does it cost?** ₪457 with free shipping
- **Is it available?** Yes, in stock and ready to ship
- **Where can I buy it?** [www.desertcart.co.il](https://www.desertcart.co.il/products/254553883-bayer-k9-advantix-ii-flea-tick-and-mosquito-prevention-x)

## Best For

- k9 advantix enthusiasts

## Why This Product

- Trusted k9 advantix brand quality
- Free international shipping included
- Worldwide delivery with tracking
- 15-day hassle-free returns

## Key Features

- • **Fast-Acting Formula:** Begins killing fleas within 12 hours to stop infestations before they start.
- • **Ultimate Pest Defense:** Kills & repels fleas, ticks, mosquitoes, lice, and biting flies for full-spectrum protection.
- • **Waterproof & Swim-Proof:** Keeps working even after baths, swims, or rain—no reapplication needed.
- • **Vet-Recommended Reliability:** Trusted by veterinarians for safe, effective pest control on extra-large dogs over 55 lbs.
- • **Convenient Monthly Protection:** Four easy topical applications provide a full 4-month shield against pests.

## Overview

Bayer K9 Advantix II offers a powerful, vet-recommended topical solution for extra-large dogs over 55 lbs, delivering 5-way protection by killing and repelling fleas, ticks, mosquitoes, lice, and biting flies. Waterproof and fast-acting, it starts working within 12 hours and lasts 30 days per application, ensuring hassle-free, long-lasting defense even after swimming or bathing.

## Description

Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs Over 55 lb 710546040004

## Features

- New packaging, same formula: Contains four one month applications of Bayer K9 Advantix II topical flea, tick and mosquito prevention for extra large dogs over 55 pounds
- K9 Advantix II kills through contact, so fleas, ticks and mosquitoes don't have to bite your dog to die
- Veterinarian recommended
- Repels and kills fleas, ticks and mosquitoes
- Topical treatment is easy to apply, starts working to kill fleas within 12 hours and keeps working for 30 days

## Technical Specifications

| Specification | Value |
|---------------|-------|
| Brand | K9 Advantix |
| Model Number | 710546040004 |
| Product Dimensions | 19.69 x 2.54 x 10.8 cm; 45.36 g |
| Item Weight | 45.4 g |

## Product Details

- **Brand:** K9 Advantix
- **Item form:** Topical
- **Scent:** water
- **Item weight:** 0.1 Pounds
- **Active Ingredients:** Imidacloprid, Permethrin, Pyriproxyfen

## Images

![Bayer K9 Advantix II Flea, Tick and Mosquito Prevention for X-Large Dogs, Over 55 lbs Over 55 lb 710546040004 - Image 1](https://m.media-amazon.com/images/I/71cpzdT1OpL.jpg)

## Questions & Answers

**Q: Has anyone switched over from Frontline Plus to K9 Advantix II and is happy? For Dogs**
A: YES!!!!  I've had the same experience with my dogs as Nicole A replied.  I had been pleased with Frontline for years....but in 2012 (and ever since) it has just stopped working.  One of my dogs is a fur-making machine: and fleas don't seem to bother him...even if I am finding them on him.  The other dog has horrible flea allergies:  has immediate, sustained, and severe "hot spots" after even just ONE flea bite...skin will turn pink all over his body...and he "blows" large amounts of his beautiful, lush, scruffy coat...and he just doesn't seem to be his usual happy, bright, and enthusiastic self :-(   Using Advantix II....he seems to not have problems at all (it keeps the fleas from breeding...although if one occasional transient flea bites him....it will die...but the dog will still get a "hotspot", but nowhere as intense or sustained as without Advantix II...and if I find it quickly and clean it with vinegar, he may not even need a dose of benedryl).  During the "flea season" since using Advantix II he has been able to keep his lush coat with no problems.....to such an extent that I brought him in to my vet's office just to show the vet how well he was doing one summer (the dog had been so bad the previous summer while using Frontline that I had to take him to the vet for skin reactions, fur loss in large areas of his coat, and a secondary infection from scratching...I had been so discouraged about the flea problems that year while on Frontline that I had been taking the dog daily to the lake so he could swim and drown the damned fleas).  The vet was very pleased with the dog's condition with Advantix II, and had stated he has learned from his patients that they are also seeing less effectiveness with Frontline in recent years.  I won't use anything else but Advantix II during this up-coming flea season.  (although I do also spray his coat/skin with vinegar (mixed 1/2 with water) each day as a flea deterrent...especially if he gets a hotspot...and I add a small amount of vinegar to his food as well........and when he does need a bath:  I use EXTREMELY diluted Dr. Bronner's castile liquid soap in the "EUCALYPTUS" version....the dog tolerates it well...and it seems the scent repels fleas a bit.   I use the soap as well to launder the cover of his dog bed at least weekly).   I know that insects can get resistent to certain pesticides over time....and I suspect that is why Frontline no longer works in our area.....I sure hope it doesn't eventually happen with Advantix II as well....and I hope that producers of flea/tick products for dogs will monitor this situation and re-formulate their products as needed to address the situation--regionally if need be.

**Q: I thought I was ordering Advantage II but by mistake, ordered Advantix II.  What is the difference, and does it work the same?**
A: You can’t use advantix on cats.  sadly because advantix 2 is superior and is the best out there because unlike advantage (and unlike frontline) it repels flies and mosquitoes as well as ticks and fleas.  but it is toxic to cats.  as cats should be indoors only you shouldn’t need tick/mosquito repellent just flea.  DO NOT USE ADVANTIX ON CATS!  It is toxic to them

**Q: What about cats? I used to use Advantix on my cats with no problems, as suggested by my vet to save money. Has the formula changed?**
A: Look at the active ingredients for both the dog & cat formulas; They are exactly the same. Only difference is the dosage size which you can easily look up on the internet & save yourself a ton of money

**Q: Could I use this along with a flea/tick collar?**
A: As a vet tech we say a flea collar is basically worthless..At most may keep fleas off pets head. If you can buy flea collar at store probably won’t work and even the script only work minimal. Stick to topical like frontline plus, advantage, advantix and oral like Capstar. Flea collars are most always a waste of $. To remove fleas fast simply bathe dog and let dog sit in water…drowning fleas and follow up in few hours with topical if bad infestation. Just a flea or 2 I’d still bathe but topical probably enough. All topicals are water resistant after 24hr

## Frequently Bought Together

- K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 4-Mo Supply
- K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply
- K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 4-Mo Supply

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*Product available on Desertcart Israel*
*Store origin: IL*
*Last updated: 2026-02-15*