How do you know what size to buy?

Image 2 has a sizing chart but the preferred method is definitely buying the trial sizing pack initially to determine fit.

Do these help with perfume?

I never tried the nose filters with perfume but I would be skeptical. They are hard to put in your nose and they block your nose from getting air. I bought them to reduce pollen when I was cutting my lawn. I found myself breathing through my month instead of my nose. They also have a tendency to fall out. Hope this helps

Does it filter the flu virus?

i believe that it might minimize the virus from entering your body. It will definitely help rather than not.

Could these reduce the inhalation of chlorine in swimming pools?

These answers Lolol. I believe the asker is questioning if they will filter chlorine vapors from the air NOT the water. The answer is, it is unlikely. It takes a filter with a smaller micron filtering capability to filter things like vapors in my experience. It might help, but doubtful it would completely eliminate.

O2 Nose Filters with 3M Filtration - Nasal Screens for Allergies, Dust & Smoke - Drug-Free & Latex-Free Nose Filters - Invisible Allergy Protection (Large x 20)

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